Alleviation of poverty and achievement of zero-hunger target and food security are significant challenges faced by agricultural
planners worldwide. Improving many agronomic approaches, which have drastic effects on crop growth and yield, is urgently
needed to report this aim. Replacement of a part of chemical fertilizers by organic manure through a simple technique of using
minimum effective dose of sufficient and balanced quantities of organic and inorganic fertilizers in combination with specific
microorganisms, called INM, has a bright solution in this area. Recently, several investigators reported that integrated use of
chemical fertilizers with organic manure is becoming a quite promising practice not only for maintaining higher productivity but
also for greater stability to crop production. In addition, INM acts as a source of energy, organic carbon, and available nitrogen for
the growth of soil microbes and improvement of physical properties of soil, and also have great residual effect on subsequent crops.
So, the key component of the INM goal is to reach the eco-friendly practice through the harmonious properties of both sources by
making a combination that can be used for decreasing the enormous use of chemical fertilizers and accreting a balance between
fertilizer inputs and crop nutrient requirement, maintaining the soil fertility, optimizing the level of yield, maximizing the
profitability, and subsequently reducing the environmental pollution. Lastly, INM is a tool that can offer good options and
economic choices to supply plants with a sufficient amount of nutrients in need and can also reduce total costs, create favorable
soil physiochemical conditions and healthy environment, eliminate the constraints, safeguard the soil nutrient balance, and find
safety methods to get rid of agriculture wastes.