Item Details

Title: Oostatic and trypsin modulating effects of AEDES-TMOF peptide and peptide-mimics on the mosquito, Aedes aegypti Linnaeus and the stable fly, Stomoxys calcitrans Linnaeus

Date Published: 2000
Author/s: Okedi Loyce Martha Alungat
Data publication:
Funding Agency :
Copyright/patents/trade marks:
Journal Publisher:
Affiliation: University of Florida
Keywords: Animal feeding behavior, Blood, Digestion, Eggs, Enzymes, Female animals, Insects, Midgut, Oocytes, Ovaries


The decapeptide trypsin modulating oostatic factor
(TMOF) is oostatic when introduced too early in a gonotrophic cycle of the female mosquito, Aedes aegypti. The possibility that Aedes-TMOF-derived synthetic peptides
and peptide mimics may affect egg development through
modulating trypsin biosynthesis was evaluated in the mosquito, A. aegypti and on the stable fly, S. calcitrans. Additionally, a search for an ovary-derived factor similar
in properties to the Aedes-TMOF was conducted. Oostatic
activity in Aedes-TMOF peptides and peptide mimics varied
from being oostatic to toxic to no effect.